hCG and Hyperglycosylated hCG Carbohydrate Structure Corrected
نویسندگان
چکیده
منابع مشابه
Hyperglycosylated hCG.
Hyperglycosylated hCG (hCG-H) is a glycosylation variant of the hormone hCG. Here we review all that is known about this independently functioning molecule. As discussed, it is a very different molecule to the hormone hCG. First, hCG-H is produced by cytotrophoblast cells while regular hCG is made in syncytiotrophoblast cell. Second, it is an autocrine acting directly on the cells which produce...
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Purpose: Trophoblastic cancers (Choriocarcinoma, testicular and ovarian germ cell malignancies) secrete hyperglycosylated hCG and non-trophoblastic cancers secrete hyperglycosylated hCG free βsubunit.Both are structural variants of hCG independent to the hormone hCG. They are autocrines acting on a transforming growth factor β-II (TGF-β-II), receptor not acting on the hormone receptor. Here the...
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The evolution of regular chorionic gonadotropin (CG) and hyperglycosylated CG are linked with the evolution of hemochorial placentation in primates. Recent research with humans shows that regular CG promotes spiral artery angiogenesis and hyperglycosylated CG controls invasion by implanting trophoblast cells. It is inferred that the evolution of regular CG and hyperglycosylated CG in early simi...
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hCG exists in two analogous structures, as typified by the hormone hCG which binds an LH/hCG hormone receptor and the TGFß receptor binding autocrine hyperglycosylated hCG. Both share a common α-subunit and ß-subunit amino acid sequence. From the common hormone hCG and autocrine hyperglycosylated hCG structures there are seven common hCG variants with wildly varying hormone hCG or autocrine hyp...
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Deep B and R images of three Hickson Compact Groups, HCG 79, HCG 88 and HCG 95, were analyzed using a new wavelet technic to measure possible intra-group diffuse light present in these systems. The method used, OV WAV, is a wavelet technic particularly suitable to detect low-surface brightness extended structures, down to a S/N = 0.1 per pixel, which corresponds to a 5-σ-detection level in wave...
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ژورنال
عنوان ژورنال: Journal of Glycobiology
سال: 2015
ISSN: 2168-958X
DOI: 10.4172/2168-958x.1000114